Molecular Profile
What Is MOTS-c?
TypeMitochondrial-derived peptide
Amino Acids16
SequenceMRWQEMGYIFYPRKLR
Molecular Weight2,174.6 g/mol
FormulaC101H152N28O22S2
Encoded in12S rRNA (mtDNA)
⚠️ FOR RESEARCH PURPOSES ONLY — This compound is not FDA approved. All data presented is from clinical trials for educational reference.
Metabolic & Longevity Peptide
MOTS-C
4.8 (238 reviews)
Mitochondrial ORF of the 12S rRNA type-cMRWQEMGYIFYPRKLR
A mitochondrial-derived peptide that modulates metabolic processes, with significant implications for exercise metabolism observed in rodent studies. Premium Research Peptide.
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$39.99Dosage
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$39.99Thu, Apr 9 - Wed, Apr 15
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MOTS-C$39.99
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Certificate of Analysis
Third Party Tested by Freedom Diagnostics
Compound Information
Technical specifications
Cell Metabolism 2015
Storage Requirements
Stability Information
Extremely temperature sensitiveStore frozen until useReconstitute immediately before injection
Lyophilized (powder)
-20°C•stable long-term
Reconstituted
2-8°C•use immediately
Room temperature
Degrades 85-90% in 2-3 hrs
Development Status
Where It Stands
Preclinical researchCB4211 Phase 1bWADA prohibited
DiscoveryPinchas Cohen, USC 2015
Primary researchExercise mimetic / longevity
Analog in trialsCB4211 for NAFLD
Current statusResearch compound only
Sources & References
Peer-reviewed research
Cell Metabolism
The Mitochondrial-Derived Peptide MOTS-c Promotes Metabolic Homeostasis and Reduces Obesity and Insulin Resistance
2015•DOI: 10.1016/j.cmet.2015.02.009•PMID: 25738459
Lee C, Zeng J, Drew BG et al.
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Nature CommunicationsMOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and muscle homeostasis
2021•DOI: 10.1038/s41467-020-20790-0
Reynolds JC, Lai RW, Woodhead JST et al.
View Source
⚠️Important Research Notice
Not for human consumption. This product is sold exclusively for research and educational purposes. It is not intended to diagnose, treat, cure, or prevent any disease.
All clinical trial data and research findings presented on this page are sourced from peer-reviewed journals and official publications. They are provided for educational reference only and should not be interpreted as medical advice or product claims.
By purchasing this product, you confirm that you are a qualified researcher and will use it in accordance with all applicable laws and regulations.
