What Is ARA-290?
An 11-residue synthetic peptide modeled on the helix-B surface of erythropoietin. It selectively engages the innate repair receptor (a heterodimer of the EPO receptor and the beta-common receptor, CD131) without activating the classical EPO receptor homodimer, so it carries no erythropoietic activity.
- Type
- EPO-derived tissue-protective peptide
- CAS Number
- 1208243-50-8
- Molecular Weight
- ~1257 Da
- Amino Acids
- 11 (linear)
- Sequence
- pGlu-Glu-Gln-Leu-Glu-Arg-Ala-Leu-Asn-Ser-Ser
- Receptor
- Innate repair receptor (EPOR/βcR)








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