Molecular Profile
What Is KPV?
TypeSynthetic tripeptide
SequenceLys-Pro-Val (KPV)
Amino acids3
Molecular formulaC₁₆H₃₀N₄O₄
Molecular weight342.43 g/mol
CAS Number67727-97-3
Originα-MSH residues 11-13
⚠️ FOR RESEARCH PURPOSES ONLY — This compound is not FDA approved. All data presented is from clinical trials for educational reference.
Cellular Peptide
KPV
Lysine-Proline-ValineAlpha-MSH (11-13)α-MSH C-Terminal FragmentCAS: 67727-97-3
"A 3-amino acid tripeptide (Lys-Pro-Val) derived from the C-terminus of alpha-melanocyte-stimulating hormone that inhibits NF-κB activation via PepT1-mediated cellular uptake in preclinical inflammatory research models. Premium Research Peptide.
Dosage
Quantity
1
$39.99
Dosage
Quantity
1
$39.99
Thu, Apr 30 - Wed, May 6
Overnight shipping available
We accept
KPV$39.99
Free shippingon orders over $150
Damageprotection
Secure checkout256-bit SSL
Certificate of Analysis
Third Party Tested by Freedom Diagnostics
Compound Information
Technical specifications
PubChem Database
Parent Compound
Relationship to α-MSH
Parent peptideα-Melanocyte-Stimulating Hormone
α-MSH length13 amino acids
KPV positionC-terminal (11-13)
Activity retainedAnti-inflammatory effects
MCR bindingNOT required for activity
Storage Requirements
Stability Information
Freeze for storageRefrigerate after reconstitutionProtect from light
Lyophilized (powder)
-20°C long-term
Reconstituted
2-8°C•use within 7 days
Light protection
Store away from light
Sources & References
Peer-reviewed research
Gastroenterology
PepT1-Mediated Tripeptide KPV Uptake Reduces Intestinal Inflammation
2008•DOI: 10.1053/j.gastro.2007.10.026•PMID: 18061177
Dalmasso G, Charrier-Hisamuddin L, Nguyen HT, et al.
View Source
British Journal of Pharmacologyα-MSH Related Peptides: A New Class of Anti-Inflammatory and Immunomodulating Drugs
2000•DOI: 10.1111/j.1476-5381.2000.00178.x
Luger TA, Brzoska T, Scholzen TE, et al.
View Source
Molecular PharmaceuticsOrally Targeted Delivery of Tripeptide KPV via Hyaluronic Acid-Functionalized Nanoparticles Efficiently Alleviates Ulcerative Colitis
2017•PMID: 28548842
Xiao B, Xu Z, Viennois E, et al.
View Source
Annals of the New York Academy of SciencesMelanocortin-Derived Tripeptide KPV Has Anti-Inflammatory Potential in Murine Models of Inflammatory Bowel Disease
2008•PMID: 18226903
Kannengiesser K, Maaser C, Heidemann J, et al.
View Source
Journal of Investigative Dermatology
Alpha-Melanocyte-Stimulating Hormone and Related Tripeptides: Biochemistry, Antiinflammatory and Protective Effects
1999
Brzoska T, Luger TA, Maaser C, et al.
⚠️Important Research Notice
Not for human consumption. This product is sold exclusively for research and educational purposes. It is not intended to diagnose, treat, cure, or prevent any disease.
All clinical trial data and research findings presented on this page are sourced from peer-reviewed journals and official publications. They are provided for educational reference only and should not be interpreted as medical advice or product claims.
By purchasing this product, you confirm that you are a qualified researcher and will use it in accordance with all applicable laws and regulations.
